Ajcn28674g 1468..1473
نویسنده
چکیده
Recent progress in the measurement of the bioconversion of dietary provitamin A carotenoids to vitamin A is reviewed in this article. Methods to assess the bioavailability and bioconversion of provitamin Acarotenoids have advanced significantly in the past 10 y, specifically through the use of stable isotopemethodology, which includes the use of labeled plant foods. The effects of the foodmatrix on the bioconversion of provitamin A carotenoids to vitamin A, dietary fat effects, and the effect of genotype on the absorption andmetabolismofb-carotene have been reported recently. A summary of the major human studies that determined conversion factors for dietary b-carotene to retinol is presented here, and these data show that the conversion efficiency of dietary b-carotene to retinol is in the range of 3.6–28:1 by weight. There is a wide variation in conversion factors reported not only between different studies but also between individuals in a particular study. These findings show that the vitamin A value of individual plant foods rich in provitamin A carotenoids may vary significantly and need further investigation. Am J Clin Nutr 2010;91(suppl):
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